en روانشناسی Psychology پژوهشي Research <strong>Background and Objective</strong>: Adolescence is a critical period for shaping personality, career interests, and decision-making. This study aimed to compare the effectiveness of acceptance and commitment therapy (ACT) and reality therapy (RT) in improving anxiety and career path decision-making self-efficacy (CDSE) in female adolescents in Yazd City.<br> <strong>Materials & Methods</strong>: This quasi-experimental study, conducted in Yazd, Iran, during 2022-2023, utilized a pre-post-test design with a control group. Forty-five female high school students were divided into three groups: ACT, RT, and control (15 per group). Participants completed the Beck anxiety inventory (BAI) and the CDSE scale before and after the interventions. The ACT and RT groups received 90-minute weekly sessions for two months, while the control group received no intervention. Data were analyzed by SPSS software, version 23 using multivariate and univariate covariance analyses.&nbsp;<br> <strong>Results</strong>: The control group had significantly higher anxiety scores than both the ACT (mean difference=-11.089, P=0.005) and RT (mean difference=-9.806, P=0.008) groups, with no significant difference between ACT and RT (P=1.000). Only the RT group showed a significant improvement in CDSE compared to the control group (mean difference=5.990, P=0.010). Multivariate analyses confirmed the overall effectiveness of the interventions, with treatment explaining 27% of the variance in anxiety and 44% in CDSE.&nbsp;<br> <strong>Conclusion</strong>: Both ACT and RT reduced anxiety in female adolescents; however, only RT significantly improved CDSE. These findings suggest using ACT for anxiety management and RT for CDSE. Future research should explore long-term effects and potential combined therapeutic approaches.&nbsp;<br> &nbsp; Acceptance and commitment therapy (ACT), Anxiety, Career path decision-making self-efficacy (CDSE), Reality therapy (RT) 197 204 http://cpr.mazums.ac.ir/browse.php?a_code=A-10-232-1&slc_lang=en&sid=1 Farzaneh Alsadat Razavi Alesdatf@gmail.com 10031947532846002369 0009-0001-3099-5454 Yes Department of Counselling, Faculty of Humanities, Yazd Branch, Islamic Azad University, Yazd, Iran. ElahehalSadat Salari itselaheh.salari@gmail.com 10031947532846002370 0009-0005-9808-5018 No Department of Counselling, Faculty of Humanities, Yazd Branch, Islamic Azad University, Yazd, Iran. Mohammad Esmail Ebrahimi mse58_2007@yahoo.com 10031947532846002371 10031947532846002371 No Department of Psychology, Faculty of Humanities, Hamadan Branch, Islamic Azad University, Hamadan, Iran. Najmeh Sedrpoushan 10031947532846002372 10031947532846002372 No Department of Counselling, Faculty of Humanities, Yazd Branch, Islamic Azad University, Yazd, Iran.